Nearly half of Ultrio plus NAT non-discriminated reactive blood donors were identified as occult HBV infection in South China
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چکیده
منابع مشابه
occult hbv infection in rafsanjanese blood donors
objective: occult hepatitis b infection is a form of hepatitis in which despite of absence of detectable hbsag, hbv-dna is present in peripheral blood of patients. this clinical form of b hepatitis creates some problems for the iranian blood transfusion services. therefore, the aim of this study was the evaluation of status of occult hepatitis b infection in the rafsanjanese blood donors. mate...
متن کاملHBV vaccination of HCV-infected patients with occult HBV infection and anti-HBc-positive blood donors.
Anti-HBc positivity is a frequent cause of donation rejection at blood banks. Hepatitis B virus (HBV) infection may also occur in HBsAg-negative patients, a situation denoted occult infection. Similarly, very low levels of HBV-DNA have also been found in the sera of patients with chronic hepatitis C virus (HCV) infection, even in the absence of serum HBsAg. Initially we searched for HBV-DNA in ...
متن کاملThree-Year Experience in NAT Screening of Blood Donors for Transfusion Transmitted Viruses in Croatia.
Background Croatia implemented individual donation (ID)-NAT testing of blood donors in 2013 for three viruses HBV, HCV, and HIV-1 as a mandatory test for all blood donors. This study assessed the impact of NAT screening 3 years after its implementation. Methods A total of 545,463 donations were collected and screened for HBV, HCV, and HIV-1 using the Procleix Ultrio Plus Assay. All initially ...
متن کاملComparative evaluation of a triplex nucleic acid test for detection of HBV DNA, HCV RNA, and HIV-1 RNA, with the Procleix Tigris System.
Nucleic acid testing (NAT) is valuable for screening blood donors for occult hepatitis B virus (HBV) infection and infection during the window period in countries where HBV is endemic, such as China. An "in-house" NAT (Triplex NAT) was developed for screening for HBV DNA, hepatitis C virus (HCV) RNA, and the human immunodeficiency virus type 1 (HIV-1) RNA. Using the Triplex NAT, a head-to-head ...
متن کاملPrevalence of Occult Hepatitis B Infection among HBsAg Negative Blood Donors in Golestan Province
Background and Aims: Occult hepatitis B virus infection (OBI) is known as an important source of hepatitis B virus (HBV) infection. It is categorized as Hepatitis B surface antigen (HBsAg) not being present and low DNA viral load in serum. In this study, an attempt was made to investigate the outbreak of anti-HBc and OBI among the HBsAg-negative donors in Golestan province. Materials and Metho...
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2019
ISSN: 1471-2334
DOI: 10.1186/s12879-019-4215-9